The DSG1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Desmoglein 1, and DSG1. This antibody recognizes Human, Mouse, and Rat antigen. The DSG1 Antibody has been validated for the following applications: ELISA, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Subunit Structure: Binds to JUP/plakoglobin.
Similarity: Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain